博士研究生——细菌生物膜分子微生物学

该博士项目专注于细菌生物膜的新兴行为，通过转录组学和共聚焦显微镜等分子技术，对这些群落在生长及感染过程中的表现进行研究。本研究旨在揭示生物膜如何偏离孤立细菌的行为特征，从而为慢性感染的治疗方法的开发提供支持。

The project: The research group of ［会员专属信息］ ( ［会员资料链接］ ) focuses on understanding the development and emergent properties of bacterial communities (called “biofilms”). Biofilms are antibiotic-tolerant bacterial communities that are the cause of many chronic and acute infections in humans, but biofilms are also a model system for understanding basic aspects of multicellular organization in living systems. Our projects utilize highly controlled laboratory experiments based on microfluidic growth systems for biofilms, and stem-cell-derived organoids and bioengineered tissues for infections. We recently made important discoveries about danger signals that trigger biofilm formation ( Nature Microbiology 2025 ) and emergent behaviors of biofilms ( Cell 2023 ) that are the basis for the PhD project. The PhD project will investigate new emergent behaviors of biofilm communities that do not occur in isolated bacterial cells. The project will utilize a variety of molecular tools to analyze, manipulate, and perturb biofilms. A particular focus will be on the use of transcriptomics, genetics, and confocal microscopy methods for investigating cellular behaviors in biofilms during biofilm growth and during infections. The exact project is flexible and will be developed together with ［会员专属信息］, depending on the strengths and interests of the PhD student. To get an overview of our lab's recent projects, take a look at our publications: ［会员资料链接］

任职要求： 我们正在寻找一位极具动力且才华横溢的博士研究生，以加入我们的实验室。所需资格：拥有分子微生物学领域的研究论文背景的硕士学位。

We offer you: We offer a fully funded PhD position in a highly interactive, multidisciplinary, and international research group at the Biozentrum. Our group brings together expertise in molecular microbiology, biophysics, as well as bioinformatics and the analysis of large datasets. Additionally, the PhD student will be part of the Swiss NCCR AntiResist consortium, with lots of opportunities for scientific exchange with colleagues in related fields. Moreover, the Biozentrum offers excellent support from various core facilities with expert staff, and a structured PhD program. Our group embraces diversity and equal opportunity. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. Basel is an international city with people from over 150 countries, located on the border where Switzerland, Germany, and France meet. Basel is home to numerous biomedical research institutions, offering outstanding opportunities for training, networking, and career development. Basel provides a high standard of living and a rich and varied cultural atmosphere. Apply ［会员资料链接］